American Airlines is planning to cut 27 routes in early 2022, mostly serving New York City according to The Points Guy:
Routes to be cut:
From Boston:
Raleigh-Durham effective January 4, 2022
From Charlotte:
Champaign/Urbana, IL effective April 5, 2022
Toledo effective April 5, 2022
From Chicago (O’Hare):
Charlottesville, VA effective April 5, 2022
From New York-LaGuardia:
Asheville effective March 27, 2022
Bangor effective January 4, 2022
Boston effective January 4, 2022
Charleston, SC effective January 4, 2022
Martha’s Vineyard effective June 17, 2022
Myrtle Beach, SC effective June 2, 2022
Nantucket effective June 17, 2022
Orlando effective January 4, 2022
Pensacola effective May 5, 2022
Philadelphia effective January 4, 2022
Portland, ME effective January 4, 2022
Savannah effective June 3, 2022
Traverse City, MI effective June 2, 2022
From New York-JFK:
Liberia, Costa Rica effective April 5, 2022
Montreal effective January 4, 2022
San Antonio effective January 4, 2022
San Jose, Costa Rica effective April 5, 2022
Toronto (Pearson) effective January 4, 2022
From Philadelphia:
Baltimore effective April 5, 2022
Charleston, WV effective April 5, 2022
Ottawa effective April 5, 2022
From Phoenix:
Vancouver effective April 5, 2022
Calgary effective April 5, 2022
Source: https://worldairlinenews.com/2021/11/16/american-to-cut-27-routes-mostly-from-new-york/